You have heard of blue moon of Kentucky? well there are apparently blue people of Kentucky.
Being part Appalachian, Kentuckians are used to inbreeding jokes. However, there
is one joke about Kentucky and inbreeding that's funny because it's true: The
story of the Blue Fugates of Troublesome Creek. The Fugates were an extended
family living in an isolated hollow in Eastern Kentucky ominously named
Troublesome Creek. Most members of the family had "hereditary
methemoglobinemia." This is an enzyme deficiency that causes a person's blood to
run vein blue as opposed to arterial red. Instead of being pink, these people
are tinted blue or purple. The condition is based on a recessive gene; the only
way to acquire it is if both your parents pass down the love. So what were the
odds of clan founder Martin Fugate taking another methemoglobinemia carrier as
his wife? He did, and they settled in Troublesome Creek sometime in the mid 19th
Century. Cousins marrying cousins was commonplace among isolated Appalachians,
so by the time a doctor discovered the Fugates in the 1960s, there were several
blue people living in the hills around Hazard.